The use of this radical-cured resin requires that you use protective equipment, such as eye protection and gloves. The chemical is highly irritating to the skin, respiratory system, and eyes. Avoid swallowing or inhaling the fumes or sprays. Always wear protective clothing, eye protection, and gloves while using this product. This article provides an overview of the effects of 3-Methacryloxypropylmethyldimethoxysilane in research studies.
Non-human research only
The SACHRP definition of “human subject” includes research involving living individuals who are exposed to a potential risk of harm or death due to a study’s procedures. Research involving non-subjects does not meet the HHS definition of research because these interactions are not systematic investigations with the intent of creating generalizable knowledge. Non-subjects are not subjects of research, but they are a part of the study and the IRB has a responsibility to protect them.
While the NIH has a clear definition of non-human research, many studies that use biospecimens or private information of humans may not meet these standards. In such cases, investigators must adhere to ethical principles set forth by professional associations, including the protection of privacy and the design of scientific studies. To apply for Non-human research only approval, researchers must fill out a Not-Human Subjects Research Request form.
Comonomer in radical cured resins
A comonomer used in radical-cured resins is 3-Methacryloxypropyltriethoxysilane. These materials are a type of crosslinking agent for acrylics and polyester. Dalian Onichem Co., Ltd. focuses on the research, development, production, and sale of organofunctional silanes. It also specializes in the production of amino silanes, a type of comonomer, which is used as a coupling agent or a crosslinker in polymeric materials. Amino silanes are used for improving adhesion to difficult surfaces, as well as promoting moisture resistance.
The addition of ring-opening monomers renders polymers shrink-free. Numerous ring-opening monomers possess volumetric expansion upon polymerization. Examples of SOC monomers are spiro-ortho carbonates. Another comonomer CAS:18297-63-7 containing a ring-opening structure is dimethylene tetraoxaspiro undecane, a six-membered oxaspiro double SOC monomer. This compound was used to increase the adhesive fracture energy in dental composites.
Effects on eyes, respiratory system and skin
Effects on eyes, respiratory system and skin were assessed in mice. The cytokine response to RSV was stimulated in infected animals by instilling the viral RNA. Several cytokine treatments reduced the level of inflammatory responses. Anticytokine treatment had no effect on viral growth in the eye and lungs, establishing the role of the cytokine response in ocular pathology. These results establish the role of the eye in the transmission of respiratory viruses, and offer novel treatment strategies.
Studies on animals have shown that this chemical can negatively affect the central nervous system. This compound impairs learning, increases risk of cancer and reduces consciousness. It is a potential carcinogen and can affect the respiratory system and liver. It also irritates the skin and eyes. It can also affect the blood forming organs.