In a recent study, researchers studied the effect of Modafinil on two types of memory. One type of memory is known as contextual fear memory, and it is thought to take place in the amygdala and hippocampus. Specifically, modafinil pre-training improved context fear memory, but did not affect tone memory. Contextual fear memory is relatively simple, and is not thought to involve working memory.
Enhances executive function
Recent research has shown that taking Modalert can improve cognitive function, particularly in alcoholic patients. It is also shown to increase resting-state functional network connectivity, a brain function associated with cognitive control. In one study, Franke AG and colleagues compared the effects of modafinil and caffeine on chess performance. Their results were published in Eur Neuropsychopharmacology. Others have reported similar results, such as research by Rattray B and Hewitt A and McKnight GC, which examined the effects of acute modafinil ingestion on the mood and physical exertion of patients.
The researchers involved 60 patients with remitted depression in a randomized, placebo-controlled study. They assessed participants’ cognitive functions using the Cambridge Neuropsychological Test Automated Battery. The results showed that modafinil significantly improved these scores compared with placebo, a group that did not receive the medication. The study also used a parallel-group, double-blind design. The primary outcome measure was neurocognitive test scores, while secondary measures included fatigue severity and anxiety ratings.
Currently, nootropic drugs such as Modalert 200 are on the market to help people concentrate, increase attention, and increase their memory. More than 22 percent of American adults have used these prescriptions at one time or another, but research on the effects of modafinil on cognitive functioning has been sparse. In fact, many of the studies conducted to date have been short-term studies that focused only on a single dose.
The results of these studies indicate that modafinil improves working memory performance in mice and rats. In addition, it improved psychosocial functioning and RT measures in depressed patients and improved performance in serial reversal discrimination tasks. Further, studies are ongoing to determine if Modvigil can help people with everyday tasks. In the meantime, it may be the perfect drug for anyone seeking a boost in memory and productivity.
While the exact mechanism of modafinil’s wakefulness-boosting effects is not known, it is thought to be related to boosting histamine levels in the brain, which prevent sleepiness and improve concentration, and to inhibit dopamine reuptake, which increases levels of the neurotransmitter serotonin. Boosting histamine also appears to improve mood and memory.
It is not known exactly how modafinil increases a person’s alertness and how long the effects last. However, in healthy subjects, Modafinil does not cause serious side effects. Researchers have conducted a study in which 243 members of Singapore’s Air Force took a single 200-mg dose and reported no significant adverse drug events. Although some studies are ongoing, the findings of these studies show that Modafinil is a safe and effective cognitive enhancer. However, it is important to know that there are side effects.
Limitations of the present study
In most articles that discuss limitations in qualitative studies, the authors explicitly or implicitly note that the sample size is small. They also discuss how the sample size poses problems for generalizability and the validity of results. While the authors of the current study recognize these problems, they couch them as limitations. The purpose of a study like this is to test a hypothesis or answer a question. Ideally, a study’s sample size is large enough to generate new themes.
The main limitations of the present study are its small sample size and its lack of generalizability. It may not be representative of all postnatal PTSD couples. It is also unlikely that key themes would have been identified if only a subset of the sample size was included. Couples who did not participate because their male partner declined to participate may have had greater difficulties in relating to their partners. Some authors attempted to maintain the credibility of the study by arguing that the results are reliable and consistent with previous relevant work.
Side effects of modafinil
Long-term side effects of Modafinil have not been fully studied. While only 1% of people who take the drug experience them, they are a cause for concern. If used long-term, it could negatively impact cognition and health. A well-designed empirical study with tens of thousands of veteran users could answer this question. A recent meta-analysis of long-term Modafinil use suggests that the risk of long-term effects is lower than that of other wakefulness-promoting drugs.
To date, no clinical trials involving modafinil have investigated whether it affects cognitive processes or underlying causes of Alzheimer’s disease. In animals, most studies have focused on high doses, and it is not clear whether or not these high-doses can affect the human brain. Nevertheless, it appears that it can improve certain types of memory and cognitive processes at low doses. In humans, this is equivalent to 100 to 200mg daily, or 1 to 3 mg/kg. To test the drug’s effects, other tasks should be used. Visit alldayawake.com for more details.